In a first-of-its-kind interview with CNN’s chief medical correspondent Dr. Sanjay Gupta, who has recently come out in support of medical marijuana, and as part of CNN’s latest installment of its medical marijuana documentary series “Weed 3,” which airs tonight at 9pm ET, President Barack Obama is expected to express his official and most progressive and vocal support yet for medical marijuana.

This comes at a time when more and more Americans support the legalization of medical marijuana, now making up a strong and steady majority that will only continue to grow in its numbers and strengthen in its impact. This unprecedented growth and momentum in support for medical marijuana has even spilled over and seeped into the U.S. political system, resulting in a near-majority of states with legal medical marijuana and a bipartisan coalition of senators and representatives introducing historic bills to reclassify marijuana at the federal level.

However, while much progress has been made, many obstacles remain and continue to stand in the way of reclassification and legalization, most notably the anti-pot lobby, including powerful pharmaceuticals and profitable prisons. Therefore it is up to us to stand up, organize together, and fight the fight that needs fighting.